Exploring the Impact of COVID-19-Related Smell Disorders

Role: data analysis and science communication
Collaborators: This project was conducted within the NEUROPOP team at CRNL.
Scientific Objectives
The loss of smell due to COVID-19 was a key symptom, but its broader consequences remained understudied. This research aimed to:
- Analyze the consequences of smell loss on daily life and well-being.
- Determine symptom onset sequences and their relationship to recovery duration.
- Investigate the long-term effects of olfactory dysfunction on eating behavior and safety.
Challenges
Research on the loss of smell due to COVID-19 presented several challenges:
- Urgency of the pandemic : The need for rapid data collection and analysis required efficient coordination and real-time collaboration among international researchers.
- Variability in self-reported data : Differences in symptom descriptions across individuals and languages made standardization a key challenge.
- Multidisciplinary approach : Combining expertise from neuroscience, epidemiology, and data science was essential but required integrating diverse methodologies and perspectives.
Contributions
Our research introduced several novel approaches to studying COVID-19-related smell disorders:
- Impact on quality of life : The study revealed gender and age-related disparities in prolonged anosmia recovery, linking it to changes in eating habits and potential safety concerns.
- Data-driven symptom progression analysis : By leveraging sequence mining techniques, we identified patterns in symptom onset and recovery, providing insights for targeted medical interventions.
Dissemination and Publications
Journal Publication
📄 Camille Ferdenzi, Christophe Bousquet, Pierre-Emmanuel Aguera, Morgane Dantec, Christelle Daudé, Lesly Fornoni, Arnaud Fournel, Aurélien Kassan, Marylou Mantel, Maëlle Moranges, et al (2021). Recovery from COVID-19-related olfactory disorders and quality of life: insights from an observational online study. Chemical Senses.
Public Science Communication
🎥 Animated Video Series, published on the GDRO3 website